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Amanita Muscaria vs Psilocybin: They Are Not the Same Mushroom
Both are "magic mushrooms" in casual use. Pharmacologically they could not be more different. Psilocybin acts on serotonin. Amanita acts on GABA and glutamate
Microdose vs Macrodose for Depression: Different Logic, Different Evidence
The same molecule at two scales does very different things. Microdose plays a long, subtle game grounded in survey data. Macrodose plays a single
Psilocybin vs Ketamine for Depression: Different Drugs, Different Tools
Both have rapid antidepressant effects. They work through different receptor systems, have different access realities, and fit different clinical pictures. For treatment-resistant depression the
Psilocybin vs LSD: Same Receptor, Different Tool
Both are 5-HT2A agonists. Both produce the classical psychedelic experience. The differences (duration, dose precision, headspace, microdosing fit) are practical rather than mechanistic. Here
Coming soon
Psilocybin vs MDMA for trauma · Ayahuasca vs psilocybin · Lemon tek vs dried mushrooms · Psilocybin vs SSRI for depression · LSD vs psilocybin for microdosing.
